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Cellular and Molecular Neuroscience Research Axis

Dr. Armen Saghatelyan

Canada Research Chair in postnatal neurogenesis

Département de Psychiatrie et Neuroscience,
Université Laval,
Centre de recherche de l'Institut universitaire en santé mentale de Québec
Quebec (Québec) G1J 2G3
Canada

Tel. : 1 (418) 663 5321 ext. 4787
Fax. : 1 (418) 663 8756

armen.saghatelyan@crulrg.ulaval.ca

Research team

Master Degree
Helia Tenza

Ph.D.
Vincent Breton-Provencher, Archana Gengatharan, Lynda Suzanne David, Delphine Hardy, Karen Bakshetyan

Research assistant
Marina Snapyan, Caroline Gagnon

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Research areas

postnatal neurogenesis, olfaction, stem cells, neurodegenerative disease, migration, cell replacement therapy, maturation, electrophysiology, synaptic physiology, two-photon imaging

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Technology

Electrophysiologie, real-time widefield and 2photon imaging, cell culture, immunohistochemistry, in situ hydridization, stereotaxic injecyion

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Projects

Cellular and molecular mechanisms of adult neurogenesis

Adult neurogenesis in cell replacement therapies

Functional role of adult olfactory bulb neurogenesis

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Scholarships and grants

Juin 2011 - Juin 2016 : NSERC, "The role of newborn neurons in the adult olfactory bulb" (Principal investigator)

Septembre 2010 - Septembre 2015 : CIHR, "Vasculature-guided migration of neuronal precursors in the postnatal brain: From development to disease" (Principal investigator)

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Recent publications

Brain-derived neurotrophic factor promotes vasculature-associated migration of neuronal precursors toward the ischemic striatum. S Grade, YC Weng, M Snapyan, J Kriz, JO Malva, A Saghatelyan , PLoS One (2013) , Volume 8 (Issue 1) , pages e55039

The extracellular matrix glycoprotein tenascin-R affects adult but not developmental neurogenesis in the olfactory bulb. LS David, M Schachner, A Saghatelyan , J Neurosci (2013) , Volume 33 (Issue 25) , pages 10324-39

Time-lapse imaging of neuroblast migration in acute slices of the adult mouse forebrain. J Khlghatyan, A Saghatelyan , J Vis Exp (2012) (Issue 67) , pages e4061

Newborn neurons in the adult olfactory bulb: unique properties for specific odor behavior. V Breton-Provencher, A Saghatelyan , Behav Brain Res (2012) , Volume 227 (Issue 2) , pages 480-9

Astrocytes control the development of the migration-promoting vasculature scaffold in the postnatal brain via VEGF signaling. L Bozoyan, J Khlghatyan, A Saghatelyan , J Neurosci (2012) , Volume 32 (Issue 5) , pages 1687-704

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